Recurrence may be due to endogenous relapse or exogenous reinfection.
Tuberculosis disease among previously treated individuals (recurrent TB) constitutes 5–30% of the TB burden, with higher proportions found in high-prevalence settings. There is an urgent need for improved understanding of propagating factors of the epidemic. Globally, the burden of disease is still very high TB notification rates are decreasing but much more slowly than needed to reach this aim. The World Health Organization launched its End TB Strategy in 2014 with the aim to cut TB incidence by 90% by 2035. Tuberculosis (TB) has seen a worldwide resurgence since the advent of the human immunodeficiency virus (HIV) epidemic in the 1990s. Antitubercular agents/therapeutic use, incidence, recurrence, South Africa, epidemiology
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